Detalhe da pesquisa
1.
Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike.
Proc Natl Acad Sci U S A
; 121(15): e2317222121, 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38557175
2.
Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains.
PLoS Biol
; 20(7): e3001738, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35895696
3.
Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATP Channel Mutations in Intact Cells.
J Pharmacol Exp Ther
; 386(3): 298-309, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37527933
4.
Mutants of human ACE2 differentially promote SARS-CoV and SARS-CoV-2 spike mediated infection.
PLoS Pathog
; 17(7): e1009715, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34270613
5.
Massively parallel variant characterization identifies NUDT15 alleles associated with thiopurine toxicity.
Proc Natl Acad Sci U S A
; 117(10): 5394-5401, 2020 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32094176
6.
An improved platform for functional assessment of large protein libraries in mammalian cells.
Nucleic Acids Res
; 48(1): e1, 2020 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31612958
7.
On the design of CRISPR-based single-cell molecular screens.
Nat Methods
; 15(4): 271-274, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29457792
8.
A platform for functional assessment of large variant libraries in mammalian cells.
Nucleic Acids Res
; 45(11): e102, 2017 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28335006
9.
Nucleoporin NUP153 phenylalanine-glycine motifs engage a common binding pocket within the HIV-1 capsid protein to mediate lentiviral infectivity.
PLoS Pathog
; 9(10): e1003693, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24130490
10.
Host and viral determinants for MxB restriction of HIV-1 infection.
Retrovirology
; 11: 90, 2014 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25348155
11.
Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integration.
J Virol
; 87(1): 648-58, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23097450
12.
Multiplex Functional Characterization of Protein Variant Libraries in Mammalian Cells with Single-Copy Genomic Integration and High-Throughput DNA Sequencing.
Methods Mol Biol
; 2774: 135-152, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38441763
13.
Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage.
bioRxiv
; 2024 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38405739
14.
Mammalian Genomic Manipulation with Orthogonal Bxb1 DNA Recombinase Sites for the Functional Characterization of Protein Variants.
ACS Synth Biol
; 12(11): 3352-3365, 2023 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37922210
15.
High-throughput functional mapping of variants in an arrhythmia gene, KCNE1, reveals novel biology.
bioRxiv
; 2023 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37162834
16.
High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike.
Nat Commun
; 14(1): 2003, 2023 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37037866
17.
Optogenetic Microwell Array Screening System: A High-Throughput Engineering Platform for Genetically Encoded Fluorescent Indicators.
ACS Sens
; 8(11): 4233-4244, 2023 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37956352
18.
The requirement for nucleoporin NUP153 during human immunodeficiency virus type 1 infection is determined by the viral capsid.
J Virol
; 85(15): 7818-27, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21593146
19.
Differential sensitivities of retroviruses to integrase strand transfer inhibitors.
J Virol
; 85(7): 3677-82, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21270168
20.
Probing the biophysical constraints of SARS-CoV-2 spike N-terminal domain using deep mutational scanning.
Sci Adv
; 8(47): eadd7221, 2022 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36417523